Article
ADAM33 and ADAM12 genetic polymorphisms and their expression in Egyptian children with asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Jan 2016
Shalaby Sally M, Abdul-Maksoud Rehab S, Abdelsalam Sanaa M, Abdelrahman Hadeel M, Abdelaziz Almalky Mohamed A
Abstract excerpt
BACKGROUND: The ADAM family is involved in some pathologic processes, such as inflammation and asthma. OBJECTIVES: To assess the association between ADAM33 and ADAM12 single-nucleotide polymorphisms (SNPs) with asthma risk and severity and to investigate the effect of ADAM33 and ADAM12 polymorphisms on expression of these proteases in sputum. METHODS: Two SNPs of the ADAM33 gene, F+1 (rs511898) G/A and ST+4...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
