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Article

Polymorphisms in metalloproteinase-9 are associated with the risk for asthma in Mexican pediatric patients.

Human immunology - 1 Aug 2013

Jiménez-Morales Silvia, Martínez-Aguilar Nora, Gamboa-Becerra Roberto, Jiménez-Ruíz Juan Luis, López-Ley Diana, Lou Hong, Saldaña-Alvarez Yolanda, Dean Michael, Orozco Lorena

Abstract excerpt

Asthma is characterized by chronic airway inflammation, which induces airway remodelling of the extracellular matrix over time. Matrix metalloproteinases (MMPs) are involved in this process, and single-nucleotide polymorphisms (SNPs) in MMP genes may influence their mRNA expression levels or abilities to bind substrates and inhibitors, thereby contributing to asthma predisposition and severity. MMP-9 is highly...

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Identifiers

PMID: 23639553
DOI: 10.1016/j.humimm.2013.04.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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