Article
ADAM33 gene polymorphisms associate with asthma susceptibility and severity in East China han population.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Dec 2011
Jie Zhijun, Hu Zhilin, Bai Chunxue, Jin Meiling
Abstract excerpt
OBJECTIVE: Multiple genetic and environmental factors impact the pathogenesis of asthma. ADAM33 (a disintegrin and metalloproteinase domain 33) represents a novel susceptibility gene for asthma in several diverse populations. The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) of the ADAM33 gene associate with asthma susceptibility and severity in the Chinese Han population....
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