Article
MaCH-admix: genotype imputation for admixed populations.
Genetic epidemiology - 1 Jan 2013
Liu Eric Yi, Li Mingyao, Wang Wei, Li Yun
Abstract excerpt
Imputation in admixed populations is an important problem but challenging due to the complex linkage disequilibrium (LD) pattern. The emergence of large reference panels such as that from the 1,000 Genomes Project enables more accurate imputation in general, and in particular for admixed populations and for uncommon variants. To efficiently benefit from these large reference panels, one key issue to consider in...
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