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Article

A generic coalescent-based framework for the selection of a reference panel for imputation.

Genetic epidemiology - 1 Dec 2010

Paşaniuc Bogdan, Avinery Ram, Gur Tom, Skibola Christine F, Bracci Paige M, Halperin Eran

Abstract excerpt

An important component in the analysis of genome-wide association studies involves the imputation of genotypes that have not been measured directly in the studied samples. The imputation procedure uses the linkage disequilibrium (LD) structure in the population to infer the genotype of an unobserved single nucleotide polymorphism. The LD structure is normally learned from a dense genotype map of a reference...

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PMID: 21058333
DOI: 10.1002/gepi.20505
PMCID: PMC3876740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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