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Article

Comparison of pharmacokinetics and pharmacogenetics of once- and twice-daily tacrolimus in the early stage after renal transplantation.

Transplantation - 27 Nov 2012

Niioka Takenori, Satoh Shigeru, Kagaya Hideaki, Numakura Kazuyuki, Inoue Takamitsu, Saito Mitsuru, Narita Shintaro, Tsuchiya Norihiko, Habuchi Tomonori, Miura Masatomo

Abstract excerpt

BACKGROUND: This study investigated pharmacokinetic and pharmacogenetic differences between a modified-release once-daily formulation of tacrolimus (Tac-QD) and the original formulation requiring twice-daily intake (Tac-BID) in de novo renal transplant recipients. METHODS: Forty-seven and 25 patients who received Tac-BID and Tac-QD, respectively, were enrolled. The pharmacokinetics and CYP3A5 6986A>G and ABCB1...

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Identifiers

PMID: 23073468
DOI: 10.1097/TP.0b013e31826bc400

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BID
ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Comparison of pharmacokinetics and pharmacogenetics of once- and twice-daily tacrolimus in the early stage after renal transplantation.PMID 23073468Read ↗

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