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Article

Gateway role for rRNA precursors in ribosome assembly.

Journal of bacteriology - 1 Dec 2012

Gutgsell Nancy S, Jain Chaitanya

Abstract excerpt

In Escherichia coli, rRNAs are initially transcribed with precursor sequences, which are subsequently removed through processing reactions. To investigate the role of precursor sequences, we analyzed ribosome assembly in strains containing mutations in the processing RNases. We observed that defects in 23S rRNA processing resulted in an accumulation of ribosomal subunits and caused a significant delay in ribosome...

Topics

Escherichia coli
Escherichia coli Proteins
Mutation
RNA Precursors
RNA Processing, Post-Transcriptional
RNA, Bacterial
RNA, Ribosomal, 23S
Ribonucleases
Ribosomal Proteins
Ribosome Subunits
Ribosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23065976
DOI: 10.1128/JB.01467-12
PMCID: PMC3510557

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