Article
Role of precursor sequences in the ordered maturation of E. coli 23S ribosomal RNA.
RNA (New York, N.Y.) - 1 Feb 2012
Gutgsell Nancy S, Jain Chaitanya
Abstract excerpt
The maturation of ribosomal RNAs (rRNAs) is an important but incompletely understood process required for rRNAs to become functional. In order to determine the enzymes responsible for initiating 3' end maturation of 23S rRNA in Escherichia coli, we analyzed a number of strains lacking different combinations of 3' to 5' exo-RNases. Through these analyses, we identified RNase PH as a key effector of 3' end...
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