Article
Association of KIBRA with episodic and working memory: a meta-analysis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2012
Milnik Annette, Heck Angela, Vogler Christian, Heinze Hans-Jochen, de Quervain Dominique J-F, Papassotiropoulos Andreas
Abstract excerpt
WWC1 was first implicated in human cognition through a genome wide association study in 2006 that reported an association of the intronic single nucleotide polymorphism (SNP) rs17070145 with episodic memory performance. WWC1 encodes the protein KIBRA, which is almost ubiquitously expressed. Together with its binding partners, KIBRA is assumed to play a role in synaptic plasticity. T-allele carriers of SNP...
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