Article
Interactive effects of KIBRA and CLSTN2 polymorphisms on episodic memory in old-age unipolar depression.
Neuropsychologia - 1 Sept 2014
Pantzar Alexandra, Laukka Erika J, Atti Anna Rita, Papenberg Goran, Keller Lina, Graff Caroline, Fratiglioni Laura, Bäckman Lars
Abstract excerpt
The KIBRA (rs17070145) C-allele and the CLSTN2 (rs6439886) T-allele have both been associated with poorer episodic memory performance. Given that episodic memory is affected in depression, we hypothesized that the combination of these risk alleles would be particularly detrimental to episodic memory performance in depressed persons. In the population-based SNAC-K study, 2170 participants (≥ 60 years) without...
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