Article
Allele-specific gene expression is widespread across the genome and biological processes.
PloS one - 1 Jan 2009
Palacios Ricardo, Gazave Elodie, Goñi Joaquín, Piedrafita Gabriel, Fernando Olga, Navarro Arcadi, Villoslada Pablo
Abstract excerpt
Allelic specific gene expression (ASGE) appears to be an important factor in human phenotypic variability and as a consequence, for the development of complex traits and diseases. In order to study ASGE across the human genome, we have performed a study in which genotyping was coupled with an analysis of ASGE by screening 11,500 SNPs using the Mapping 10 K Array to identify differential allelic expression. We...
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