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Article

Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study.

Nutrition and cancer - 1 Jan 2012

Razzak Anthony A, Oxentenko Amy S, Vierkant Robert A, Tillmans Lori S, Wang Alice H, Weisenberger Daniel J, Laird Peter W, Lynch Charles F, Anderson Kristin E, French Amy J, Haile Robert W, Harnack Lisa J, Potter John D, Slager Susan L, Smyrk Thomas C, Thibodeau Stephen N, Cerhan James R, Limburg Paul J

Abstract excerpt

Folate and related micronturients may affect colorectal cancer (CRC) risk, but the molecular mechanism(s) remain incompletely defined. We analyzed associations between dietary folate, vitamin B6, vitamin B12, and methionine with incident CRC, overall and by microsatellite instability (MSS/MSI-L or MSI-H), CpG island methylator phenotype (CIMP-negative or CIMP-positive), BRAF mutation (negative or positive), and...

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Identifiers

PMID: 23061900
DOI: 10.1080/01635581.2012.714833
PMCID: PMC3584680

Genes

BRAF
KRAS

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