Article
Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter.
Molecular microbiology - 1 Dec 2012
Lu Shuo, Zgurskaya Helen I
Abstract excerpt
MacB is a founding member of the Macrolide Exporter family of transporters belonging to the ATP-Binding Cassette superfamily. These proteins are broadly represented in genomes of both Gram-positive and Gram-negative bacteria and are implicated in virulence and protection against antibiotics and peptide toxins. MacB transporter functions together with MacA, a periplasmic membrane fusion protein, which stimulates...
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