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Article

Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli.

Science (New York, N.Y.) - 30 Nov 2012

Okuda Suguru, Freinkman Elizaveta, Kahne Daniel

Abstract excerpt

Millions of molecules of lipopolysaccharide (LPS) must be assembled on the Escherichia coli cell surface each time the cell divides. The biogenesis of LPS requires seven essential lipopolysaccharide transport (Lpt) proteins to move LPS from the inner membrane through the periplasm to the cell surface. However, no intermediate transport states have been observed. We developed methods to observe intermediate LPS...

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Identifiers

PMID: 23138981
DOI: 10.1126/science.1228984
PMCID: PMC3552488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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