Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump.

Journal of molecular biology - 17 Apr 2009

Yum Soohwan, Xu Yongbin, Piao Shunfu, Sim Se-Hoon, Kim Hong-Man, Jo Wol-Soon, Kim Kyung-Jin, Kweon Hee-Seok, Jeong Min-Ho, Jeon Hyesung, Lee Kangseok, Ha Nam-Chul

Abstract excerpt

In Gram-negative bacteria, type I protein secretion systems and tripartite drug efflux pumps have a periplasmic membrane fusion protein (MFP) as an essential component. MFPs bridge the outer membrane factor and an inner membrane transporter, although the oligomeric state of MFPs remains unclear....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aggregatibacter actinomycetemcomitans
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bacterial Outer Membrane Proteins

Share to Crystallography, X-Ray

Share to Lipoproteins

Share to Macrolides

Share to Microscopy, Electron, Transmission

Share to Protein Structure, Quaternary

Source

Identifiers

PMID: 19254725
DOI: 10.1016/j.jmb.2009.02.048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19254725-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump.PMID 19254725Read ↗

Conformational flexibility in the multidrug efflux system protein AcrA.Semantic proximity Read ↗

Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter.Semantic proximity Read ↗

A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps.Semantic proximity Read ↗

Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux PumpSemantic proximity Read ↗

Structural and functional analysis of the <i>Mycobacterium tuberculosis</i> MmpS5L5 efflux pump presages a pathway to increased bedaquiline resistanceSemantic proximity Read ↗

Purification of AcrAB-TolC Multidrug Efflux Pump for Cryo-EM Analysis.Semantic proximity Read ↗

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket.Semantic proximity Read ↗

A ban on BAM: an update on inhibitors of the β-barrel assembly machinery.Semantic proximity Read ↗

Tripartite efflux pumps of the RND superfamily: what did we learn from computational studies?Semantic proximity Read ↗

The RND efflux pump EefABC is highly conserved within lineages of <i>E. coli</i> commonly associated with infectionSemantic proximity Read ↗

Elucidating TolC Protein Dynamics: Structural Shifts Facilitate Efflux Mediated β-lactam ResistanceSemantic proximity Read ↗

Bacterial Multidrug Efflux TransportersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.