Article
Evaluation of rs62527607 [GT] single nucleotide polymorphism located in BAALC gene in children with acute leukemia using mismatch PCR-RFLP.
Cancer genetics - 1 Jan 2000
Nadimi Motahareh, Rahgozar Soheila, Moafi Alireza, Tavassoli Manoochehr, Mesrian Tanha Hamzeh
Abstract excerpt
Acute leukemia is the most common cancer in children and involves several factors that contribute to the development of multidrug resistance and treatment failure. According to our recent studies, the BAALC gene is identified to have high mRNA expression levels in childhood acute lymphoblastic leukemia (ALL) and those with multidrug resistance. Several polymorphisms are associated with the expression of this...
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