Article
Cofilin-1: a modulator of anxiety in mice.
PLoS genetics - 1 Jan 2012
Goodson Martin, Rust Marco B, Witke Walter, Bannerman David, Mott Richard, Ponting Chris P, Flint Jonathan
Abstract excerpt
The genes involved in conferring susceptibility to anxiety remain obscure. We developed a new method to identify genes at quantitative trait loci (QTLs) in a population of heterogeneous stock mice descended from known progenitor strains. QTLs were partitioned into intervals that can be summarized by a single phylogenetic tree among progenitors and intervals tested for consistency with alleles influencing anxiety...
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