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Article

High-resolution genetic mapping of complex traits from a combined analysis of F2 and advanced intercross mice.

Genetics - 1 Sept 2014

Parker Clarissa C, Carbonetto Peter, Sokoloff Greta, Park Yeonhee J, Abney Mark, Palmer Abraham A

Abstract excerpt

Genetic influences on anxiety disorders are well documented; however, the specific genes underlying these disorders remain largely unknown. To identify quantitative trait loci (QTL) for conditioned fear and open field behavior, we used an F2 intercross (n = 490) and a 34th-generation advanced intercross line (AIL) (n = 687) from the LG/J and SM/J inbred mouse strains. The F2 provided strong support for several...

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Share to Anxiety
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conditioning, Classical

Share to Hybridization, Genetic

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Identifiers

PMID: 25236452
DOI: 10.1534/genetics.114.167056
PMCID: PMC4174923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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