Article
Contribution of the TRPV1 channel to salt taste quality in mice as assessed by conditioned taste aversion generalization and chorda tympani nerve responses.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Dec 2012
Smith Kimberly R, Treesukosol Yada, Paedae A Brennan, Contreras Robert J, Spector Alan C
Abstract excerpt
In rodents, at least two transduction mechanisms are involved in salt taste: 1) the sodium-selective epithelial sodium channel, blocked by topical amiloride administration, and 2) one or more amiloride-insensitive cation-nonselective pathways. Whereas electrophysiological evidence from the chorda tympani nerve (CT) has implicated the transient receptor potential vanilloid-1 (TRPV1) channel as a major component of...
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