Article
A high-throughput screening procedure for identifying mice with aberrant taste and oromotor function.
Chemical senses - 1 Jun 2002
Glendinning John I, Gresack Jodi, Spector Alan C
Abstract excerpt
Little is known about how specific genes influence taste function in mammals. One of the most promising ways to fill this void is to screen the progeny of chemically mutagenized (or genetically altered) mice for aberrant taste phenotypes and then identify the mutated gene(s) that is associated with each taste anomaly. To exploit this approach, a high-throughput and robust screening procedure is needed. We have...
Topics
- Animals
- Dose-Response Relationship, Drug
- Female
- Male
- Mice
- Mice, Inbred C57BL
- Odorants
- Phenotype
- Quinine
- Sex Factors
- Sodium Chloride
- Statistics as Topic