Article
Do polymorphisms in the TAS1R1 gene contribute to broader differences in human taste intensity?
Chemical senses - 1 Oct 2013
Rawal Shristi, Hayes John E, Wallace Margaret R, Bartoshuk Linda M, Duffy Valerie B
Abstract excerpt
The TAS1R genes encode heterodimeric receptors that mediate umami (hTAS1R1 + hTAS1R3) and sweet (hTAS1R2 + hTAS1R3) sensations. The question of interest for this study is if TAS1R1 variation associates with differences in overall taste intensity. We leveraged an existing database of adults (n = 92, primarily European American) to test associations between 2 TAS1R1 single nucleotide polymorphisms (SNPs) (intronic...
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