Article
A psychophysical and electrophysiological analysis of salt taste in Trpv1 null mice.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 May 2007
Treesukosol Yada, Lyall Vijay, Heck Gerard L, DeSimone John A, Spector Alan C
Abstract excerpt
Current evidence suggests salt taste transduction involves at least two mechanisms, one that is amiloride sensitive and appears to use apically located epithelial sodium channels relatively selective for Na(+) and a second that is amiloride insensitive and uses a variant of the transient receptor potential vanilloid receptor 1 (TRPV1) that serves as a nonspecific cation channel. To provide a functional context...
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