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Article

Soa genotype selectively affects mouse gustatory neural responses to sucrose octaacetate.

Physiological genomics - 27 Apr 2001

Inoue M, Li X, McCaughey S A, Beauchamp G K, Bachmanov A A

Abstract excerpt

In mice, behavioral acceptance of the bitter compound sucrose octaacetate (SOA) depends on allelic variation of a single gene, Soa. The SW.B6-Soa(b)congenic mouse strain has the genetic background of an "SOA taster" SWR/J strain and an Soa-containing donor chromosome fragment from an "SOA nontaster" C57BL/6J strain. Using microsatellite markers polymorphic between the two parental strains, we determined that the...

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Identifiers

PMID: 11328963
DOI: 10.1152/physiolgenomics.2001.5.4.181
PMCID: PMC3653171

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