Article
Genetic variants in metabolizing genes NQO1, NQO2, MTHFR and risk of prostate cancer: a study from North India.
Molecular biology reports - 1 Dec 2012
Mandal Raju K, Nissar Kamran, Mittal Rama D
Abstract excerpt
Quinone oxidoreductases (NAD(P)H): quinone oxidoreductase 1 (NQO1) and NRH: quinone oxidoreductase 2 (NQO2) are an antioxidant enzyme, important in the detoxification of environmental carcinogens. Methylene-tetra-hydrofolate reductase (MTHFR), plays a role in folate metabolism and may have oncoge...
Topics
- Aged
- Bone Neoplasms
- Case-Control Studies
- Demography
- Environment
- Epistasis, Genetic
- Exons
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- India
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- NAD(P)H Dehydrogenase (Quinone)
- Neoplasm Grading
- Odds Ratio
- Polymorphism, Single Nucleotide
- Prostatic Neoplasms