Article
Genetic variants of NQO1 gene increase bladder cancer risk in Indian population and meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014
Mandal Raju K, Dubey Sandhya, Panda Aditya K, Mittal Rama D
Abstract excerpt
NAD(P)H: quinone oxidoreductase (NQO1) is cytosolic enzymes that plays a role in protection against natural and xenobiotic quinones. This enzyme also protects cells from oxidative damage by preventing the generation of reactive oxygen species and reducing environmental carcinogens. The study included 200 bladder cancer (BC) patients and 200 healthy control individuals that had been matched by age and sex, and...
Topics
- Asian People
- Exons
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- NAD(P)H Dehydrogenase (Quinone)
- Neoplasm Recurrence, Local
- Polymorphism, Single Nucleotide
- Risk Factors
- Smoking
