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Article

Analysis of relation between C677T genotype in MTHFR gene and prostatic cancer in Iranian males.

Acta medica Iranica - 1 Jan 2012

Fard-Esfahani Pezhman, Mohammadi Torbati Peyman, Hashemi Zahra, Fayaz Shima, Golkar Majid

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) enzyme is one of the most important enzymes with a pivotal role in the folate metabolism and DNA synthesis pathways. Single nucleotide polymorphism (SNPs) in the coding gene has been related to many medical diseases as well as diverse malignancies including the prostate cancer which is the leading cause of the cancer deaths in men and one of the major public health...

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Identifiers

PMID: 23275280

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of relation between C677T genotype in MTHFR gene and prostatic cancer in Iranian males.PMID 23275280Read ↗

The Analysis of the Relationship Between A1298C and C677T Polymorphisms of the <i>MTHFR</i> Gene with Prostate Cancer in Eskisehir PopulationSemantic proximity Read ↗

The MTHFR C677T polymorphism and prostate cancer risk: new findings from a meta-analysis of 7306 cases and 8062 controls.Semantic proximity Read ↗

The protective effect of methylenetetrahydrofolate reductase C677T polymorphism against prostate cancer risk: Evidence from 23 case-control studies.Semantic proximity Read ↗

MTHFR C677T polymorphism contributes to prostate cancer risk among Caucasians: A meta-analysis of 3511 cases and 2762 controls.Semantic proximity Read ↗

Association between MTHFR C677T Polymorphism and Risk of Prostate Cancer: Evidence from 22 Studies with 10,832 Cases and 11,993 Controls.Semantic proximity Read ↗

MTHFR polymorphism and the risk of prostate cancer: a meta-analysis of case-control studies.Semantic proximity Read ↗

Association between MTHFR gene polymorphisms (C677T, A1298C) and genetic susceptibility to prostate cancer: a meta-analysis.Semantic proximity Read ↗

Polymorphisms in the methylenetetrahydrofolate reductase gene and prostate cancer risk.Semantic proximity Read ↗

Effects of the MTHFR C677T polymorphism on prostate specific antigen and prostate cancer.Semantic proximity Read ↗

Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan.Semantic proximity Read ↗

Relationship between three polymorphisms of methylenetetrahydrofolate reductase (MTHFR C677T, A1298C, and G1793A) gene and risk of prostate cancer: a case-control study.Semantic proximity Read ↗

No Association Between MTHFR Gene C677T/A1298C Polymorphisms, Serum Folate, Vitamin B12, Homocysteine Levels, and Prostate Cancer in an Algerian Population.Semantic proximity Read ↗

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