Article
Investigation of NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism in prostate cancer.
Anticancer research - 1 Jan 2000
Ergen H Arzu, Gormus Uzay, Narter Fehmi, Zeybek Umit, Bulgurcuoglu Sibel, Isbir Turgay
Abstract excerpt
BACKGROUND: NAD(P)H:quinone oxidoreductase 1 (NQO1) is a part of the antioxidant defense system. NQO1 protects cells from oxidative stress by maintaining antioxidant forms of ubiquinone and vitamin E and this enzymatic activity can be sufficient to protect against carcinogenesis. Oxidative stress may contribute to carcinogenesis as an important risk factor. This study aimed to investigate the relationship between...
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