Article
Evaluation of UDP-glucuronosyltransferase 2B17 (UGT2B17) and dihydrofolate reductase (DHFR) genes deletion and the expression level of NGX6 mRNA in breast cancer.
Molecular biology reports - 1 Dec 2012
Eskandari-Nasab Ebrahim, Hashemi Mohammad, Rezaei Hamzeh, Fazaeli Aliakbar, Mashhadi Mohammad Ali, Moghaddam Simin Sargholzaei, Arbabi Farshid, Jahantigh Mahdi, Taheri Mohsen
Abstract excerpt
The present study was aimed to investigate the possible association between 19-base pair (bp) deletion polymorphism of the DHFR gene (rs70991108), null genotype of UDP-glucuronosyltransferase 2B17 (UGT2B17) as well as the expression level of nasopharyngeal carcinoma-associated gene 6 (NGX6) with the risk of breast cancer. This case-control study was done on 236 patients with breast cancer and 203 cancer free...
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