Article
Heterogeneity of peripheral blood monocyte populations in human immunodeficiency virus-1 seropositive patients.
FEMS microbiology immunology - 1 Dec 1992
Abel P M, McSharry C, Galloway E, Ross C, Severn A, Toner G, Gruer L, Wilkinson P C
Abstract excerpt
Monocytes from human immunodeficiency virus (HIV) patients have an increased heterogeneity of phenotype and function. In a study of 120 HIV patients we have demonstrated that they have normal monocyte differential counts but that with progression of the disease an increasing proportion of monocytes show phenotypic and functional evidence for activation or maturation. A proportion of the monocytes are larger, with...
Topics
- Antigens, CD
- Dinoprostone
- HIV Infections
- HIV-1
- HLA-DR Antigens
- Humans
- Interleukin-6
- Leukocyte Count
- Lymphocyte Activation
- Lymphotoxin-alpha
- Monocytes