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Article

Administration of recombinant IL-4 to humans regulates gene expression, phenotype, and function in circulating monocytes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 1992

Wong H L, Lotze M T, Wahl L M, Wahl S M

Abstract excerpt

As a multifunctional cytokine that can augment certain T cell responses, IL-4 is being evaluated currently as a possible therapeutic agent in the treatment of cancer patients. In this report, PBMC were isolated from such patients before and after IL-4 therapy and were analyzed for phenotypic and functional alterations. Differential blood counts showed that the relative percentages of lymphocytes and, to a lesser...

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PMID: 1531998

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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