Article
Phenotypic characterization of tumor associated macrophages and circulating monocytes in patients with Urothelial carcinoma of bladder.
Immunologic research - 7 Apr 2025
Singh Aishwarya, Raja David, Kaushal Seema, Seth Amlesh, Singh Prabhjot, Sharma Alpana
Abstract excerpt
OBJECTIVES: Targeting immune checkpoints has shown clinical efficacy in Urothelial carcinoma of bladder (UBC); however, a substantial percentage of patients remains unresponsive, which warrants the elucidation of novel therapeutic targets to circumvent immune suppression. Tumor associated macrophages (TAMs) are known for their indispensable role in cancer immunosuppression however, their phenotype and...
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