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Article

Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium.

Clinical pharmacology and therapeutics - 1 Nov 2018

Yee Sook Wah, Brackman Deanna J, Ennis Elizabeth A, Sugiyama Yuichi, Kamdem Landry K, Blanchard Rebecca, Galetin Aleksandra, Zhang Lei, Giacomini Kathleen M

Abstract excerpt

Advances in genomic technologies have led to a wealth of information identifying genetic polymorphisms in membrane transporters, specifically how these polymorphisms affect drug disposition and response. This review describes the current perspective of the International Transporter Consortium (ITC) on clinically important polymorphisms in membrane transporters. ITC suggests that, in addition to previously...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29679469
DOI: 10.1002/cpt.1098
PMCID: PMC6348109

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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