Article
Pharmacogenetics of membrane transporters: a review of current approaches.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Sissung Tristan M, Gardner Erin R, Gao Rui, Figg William D
Abstract excerpt
This chapter provides a review of the pharmacogenetics of membrane transporters, including adenosine triphosphate-binding cassette (ABC) transporters and organic anion transporting proteins (OATPs). Membrane transporters are heavily involved in drug disposition by actively transporting substrate drugs between organs and tissues. As such, polymorphisms in the genes encoding these proteins may have a significant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
