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Article

Canid progesterone receptors lack activation function 3 domain-dependent activity.

Endocrinology - 1 Dec 2012

Gracanin Ana, van Wolferen Monique E, Sartorius Carol A, Brenkman Arjan B, Schoonen Willem G, Mol Jan A

Abstract excerpt

Progesterone regulates multiple behavioral, physiological, and pathological aspects of female reproductive biology through its two progesterone receptors (PRs), PR-B and the truncated PR-A. PR-B is necessary for mammary gland development in mice and, compared with PR-A, is overall a stronger transactivator of target genes due to an additional activation function 3 (AF3) domain. In dogs, known for their high...

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Identifiers

PMID: 23041671
DOI: 10.1210/en.2012-1793

Genes

FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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