Article
Constitutively active FOXO1a and a DNA-binding domain mutant exhibit distinct co-regulatory functions to enhance progesterone receptor A activity.
Journal of molecular endocrinology - 1 Jun 2007
Rudd Michael D, Gonzalez-Robayna Ignacio, Hernandez-Gonzalez Inmaculada, Weigel Nancy L, Bingman William E, Richards JoAnne S
Abstract excerpt
FOXO (Forkhead box O1 transcription factors) factors interact with and modify the activity of other transcription factors, including nuclear hormone receptors. However, not all of the structural domains within the FOXO proteins that mediate these functional interactions have been clearly defined. To address this issue, we used a constitutively active (nuclear) mutant of FOXO1a (designated FOXOA3) and within...
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