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Article

microRNA-34a sensitizes lung cancer cell lines to DDP treatment independent of p53 status.

Cancer biotherapy & radiopharmaceuticals - 1 Feb 2013

Wang Xi, Dong Ke, Gao Ping, Long Min, Lin Fang, Weng Yuanyuan, Ouyang Yongri, Ren Jihong, Zhang Huizhong

Abstract excerpt

miR-34a was identified as one of the downregulated microRNAs (miRNAs) in human lung cancer. However, the precise biological role of miR-34a in p53 deficient lung cancer cell lines remains largely elusive. In the present study, we aimed to identify the role of miR-34a in the regulation of lung cancer cell proliferation. Using quantitative RT-PCR analysis, we found that miR-34a was highly upregulated in the p53...

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Identifiers

PMID: 23036084
DOI: 10.1089/cbr.2012.1218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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