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Article

Effect of microRNA-21 on multidrug resistance reversal in A549/DDP human lung cancer cells

15 Oct 2014

Abstract excerpt

Lung cancer is a predominant cause of cancer-related mortality and numerous lung cancer patients succumb to the disease due to drug resistance. A number of microRNAs (miRNAs) are upregulated in cancer and are involved in tumorigenesis, functioning as oncogenes. Several functional studies have shown that miR-21 is important in carcinogenesis; however, none of these studies has investigated multidrug resistance...

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PMID: 25323306
DOI: 10.3892/mmr.2014.2662

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