Article

Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia

2010-07-15

Abstract excerpt

Chronic lymphocytic leukemia (CLL) has an incidence 4/100 000 people in the western world and is one of the first cancers reported to be associated with deregulated miRNA expression. microRNAs are small non coding RNAs that are important regulators of protein expression through binding to their untranslated 3'-UTR region. The miR-34 family was demonstrated to be induced by the tumor suppressor p53 and to elicit p5...

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Literature Corpus work: 0130dba8-ddbd-5ce5-a357-09f48296d081
DOI: 10.4161/cc.9.14.12267

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