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Article

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis.

Molecular cell - 8 Jun 2007

Raver-Shapira Nina, Marciano Efi, Meiri Eti, Spector Yael, Rosenfeld Nitzan, Moskovits Neta, Bentwich Zvi, Oren Moshe

Abstract excerpt

p53 is a potent tumor suppressor, whose biological effects are largely due to its function as a transcriptional regulator. Here we report that, in addition to regulating the expression of hundreds of protein-coding genes, p53 also modulates the levels of microRNAs (miRNAs). Specifically, p53 can...

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Identifiers

PMID: 17540598
DOI: 10.1016/j.molcel.2007.05.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17540598-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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