Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zfp423/OAZ mutation reveals the importance of Olf/EBF transcription activity in olfactory neuronal maturation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Oct 2012

Roby Yang A, Bushey Michael A, Cheng Li E, Kulaga Heather M, Lee Se-Jin, Reed Randall R

Abstract excerpt

Zfp423/OAZ, a multi-zinc finger protein, is proposed to participate in neuronal differentiation through interactions with the Olf/EBF (O/E) family of transcription factors and mediate extrinsic BMP signaling pathways. These activities are associated with distinct domains of the Olf/EBF-associated zinc finger (OAZ) protein. Sustained OAZ expression arrests olfactory sensory neurons (OSNs) at an immature state and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Proteins
Share to Bone Morphogenetic Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helix-Loop-Helix Motifs

Share to Neurogenesis

Share to Olfactory Mucosa

Share to Olfactory Receptor Neurons

Share to Protein Interaction Mapping

Share to Receptors, Odorant

Source

Open in PubMed Open full text

Identifiers

PMID: 23035080
DOI: 10.1523/JNEUROSCI.6190-11.2012
PMCID: PMC3483594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zfp423/OAZ mutation reveals the importance of Olf/EBF transcription activity in olfactory neuronal maturation.PMID 23035080Read ↗

Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection.Semantic proximity Read ↗

The UNC-3 Olf/EBF protein represses alternate neuronal programs to specify chemosensory neuron identity.Semantic proximity Read ↗

Obox, a Family of Homeobox Genes Preferentially Expressed in Germ CellsSemantic proximity Read ↗

Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.Semantic proximity Read ↗

Mice lacking the Obox6 homeobox gene undergo normal early embryonic development and are fertile.Semantic proximity Read ↗

OBOX regulates mouse zygotic genome activation and early development.Semantic proximity Read ↗

Arx homeobox gene is essential for development of mouse olfactory system.Semantic proximity Read ↗

Canonical Wnt signaling modulates <i>Tbx1</i>, <i>Eya1</i>, and <i>Six1</i> expression, restricting neurogenesis in the otic vesicleSemantic proximity Read ↗

Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice.Semantic proximity Read ↗

Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4.Semantic proximity Read ↗

The Ets factor Spi-B is a direct critical target of the coactivator OBF-1.Semantic proximity Read ↗

The role of the OVOL1-OVOL2 axis in normal and diseased human skin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.