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Article

The role of the OVOL1-OVOL2 axis in normal and diseased human skin.

Journal of dermatological science - 1 Jun 2018

Tsuji Gaku, Ito Takamichi, Chiba Takahito, Mitoma Chikage, Nakahara Takeshi, Uchi Hiroshi, Furue Masutaka

Abstract excerpt

OVOLs (OVO-like proteins) are ubiquitously conserved genes encoding a C2H2 zinc finger transcription factor in mammals. Functional studies on OVOL1 and OVOL2 using knockout mice have suggested that these genes play a pivotal role in the development of epithelial tissues arising from germ cells; however, the role of the OVOL1-OVOL2 axis in normal and diseased tissues remains unclear. This review highlights recent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29454536
DOI: 10.1016/j.jdermsci.2018.02.005

Genes

OVOL1
OVOL2
FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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