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Article

The landscape of DNA repeat elements in human heart failure

3 Oct 2012

Abstract excerpt

BACKGROUND: The epigenomes of healthy and diseased human hearts were recently examined by genome-wide DNA methylation profiling. Repetitive elements, heavily methylated in post-natal tissue, have variable methylation profiles in cancer but methylation of repetitive elements in the heart has never been examined. RESULTS: We analyzed repetitive elements from all repeat families in human myocardial samples, and...

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PMID: 23034148
DOI: 10.1186/gb-2012-13-10-r90

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