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Long noncoding RNA dysregulation in ischemic heart failure

17 Jun 2016

Abstract excerpt

BACKGROUND: Long noncoding RNAs (lncRNAs) are non-protein coding transcripts regulating a variety of physiological and pathological functions. However, their implication in heart failure is still largely unknown. The aim of this study is to identify and characterize lncRNAs deregulated in patients affected by ischemic heart failure. METHODS: LncRNAs were profiled and validated in left ventricle biopsies of 18...

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PMID: 27317124
DOI: 10.1186/s12967-016-0926-5

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