Article
The safety of flucloxacillin in HIV-infected patients with positive HLA-B*5701 genotype.
AIDS (London, England) - 28 Jan 2013
Vera Jaime H, Naous Nadia, Mackie Nicola, Winston Alan, Cooke Graham
Abstract excerpt
Positive HLA-B*5701 genotype has recently been identified as the main genetic risk factor for flucloxacillin drug-induced liver injury (DILI). Testing for HLA-B*5701 is routine in many HIV clinics to identify those at risk of hypersensitivity reaction (HSR) to abacavir. Considering the high prevalence of soft-tissue infections in HIV patients, we conducted a retrospective study to investigate whether...
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