Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amplified and homozygously deleted genes in glioblastoma: impact on gene expression levels.

PloS one - 1 Jan 2012

Crespo Inês, Tão Hermínio, Nieto Ana Belen, Rebelo Olinda, Domingues Patrícia, Vital Ana Luísa, Patino Maria del Carmen, Barbosa Marcos, Lopes Maria Celeste, Oliveira Catarina Resende, Orfao Alberto, Tabernero María Dolores

Abstract excerpt

BACKGROUND: Glioblastoma multiforme (GBM) displays multiple amplicons and homozygous deletions that involve relevant pathogenic genes and other genes whose role remains unknown. METHODOLOGY: Single-nucleotide polymorphism (SNP)-arrays were used to determine the frequency of recurrent amplicons an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Chromosomes, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Neoplastic

Share to Glioblastoma

Share to Homozygote

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 23029397
DOI: 10.1371/journal.pone.0046088
PMCID: PMC3460955

Genes

EGFR
MTAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23029397-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amplified and homozygously deleted genes in glioblastoma: impact on gene expression levels.PMID 23029397Read ↗

Detailed characterization of alterations of chromosomes 7, 9, and 10 in glioblastomas as assessed by single-nucleotide polymorphism arrays.Semantic proximity Read ↗

High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray.Semantic proximity Read ↗

Correlation analysis between single-nucleotide polymorphism and expression arrays in gliomas identifies potentially relevant target genes.Semantic proximity Read ↗

Identification of novel candidate target genes in amplicons of Glioblastoma multiforme tumors detected by expression and CGH microarray profiling.Semantic proximity Read ↗

Distribution and favorable prognostic implication of genomic EGFR alterations in IDH-wildtype glioblastoma.Semantic proximity Read ↗

An integrative characterization of recurrent molecular aberrations in glioblastoma genomes.Semantic proximity Read ↗

New pattern of EGFR amplification in glioblastoma and the relationship of gene copy number with gene expression profile.Semantic proximity Read ↗

Genome-wide allelotype study of primary glioblastoma multiforme.Semantic proximity Read ↗

Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenograftsSemantic proximity Read ↗

Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas.Semantic proximity Read ↗

Integrated analysis of mutations, miRNA and mRNA expression in glioblastoma.Semantic proximity Read ↗

Comparison of Biomarker Assays for EGFR : Implications for Precision Medicine in Patients with GlioblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.