Article
The unique GGA clathrin adaptor of Drosophila melanogaster is not essential.
PloS one - 1 Jan 2012
Luan Shan, Ilvarsonn Anne M, Eissenberg Joel C
Abstract excerpt
The Golgi-localized, γ-ear-containing, ARF binding proteins (GGAs) are a highly conserved family of monomeric clathrin adaptor proteins implicated in clathrin-mediated protein sorting between the trans-Golgi network and endosomes. GGA RNAi knockdowns in Drosophila have resulted in conflicting data concerning whether the Drosophila GGA (dGGA) is essential. The goal of this study was to define the null phenotype...
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