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Article

Multiple loci associated with renal function in African Americans.

PloS one - 1 Jan 2012

Shriner Daniel, Herbert Alan, Doumatey Ayo P, Zhou Jie, Huang Hanxia, Erdos Michael R, Chen Guanjie, Gerry Norman P, Christman Michael F, Adeyemo Adebowale, Rotimi Charles N

Abstract excerpt

The incidence of chronic kidney disease varies by ethnic group in the USA, with African Americans displaying a two-fold higher rate than European Americans. One of the two defining variables underlying staging of chronic kidney disease is the glomerular filtration rate. Meta-analysis in individuals of European ancestry has identified 23 genetic loci associated with the estimated glomerular filtration rate (eGFR)....

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Source

Open in PubMed Open full text

Identifiers

PMID: 23028791
DOI: 10.1371/journal.pone.0045112
PMCID: PMC3441677

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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