Article
An integrated genomic and expression analysis of 7q deletion in splenic marginal zone lymphoma.
PloS one - 1 Jan 2012
Watkins A James, Hamoudi Rifat A, Zeng Naiyan, Yan Qingguo, Huang Yuanxue, Liu Hongxiang, Zhang Jianzhong, Braggio Esteban, Fonseca Rafael, de Leval Laurence, Isaacson Peter G, Wotherspoon Andrew, McPhail Ellen D, Dogan Ahmet, Du Ming-Qing
Abstract excerpt
Splenic marginal zone lymphoma (SMZL) is an indolent B-cell lymphoproliferative disorder characterised by 7q32 deletion, but the target genes of this deletion remain unknown. In order to elucidate the genetic target of this deletion, we performed an integrative analysis of the genetic, epigenetic, transcriptomic and miRNomic data. High resolution array comparative genomic hybridization of 56 cases of SMZL...
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