Article
Conditional Sox9 ablation reduces chondroitin sulfate proteoglycan levels and improves motor function following spinal cord injury.
Glia - 1 Feb 2013
McKillop William M, Dragan Magdalena, Schedl Andreas, Brown Arthur
Abstract excerpt
Chondroitin sulfate proteoglycans (CSPGs) found in perineuronal nets and in the glial scar after spinal cord injury have been shown to inhibit axonal growth and plasticity. Since we have previously identified SOX9 as a transcription factor that upregulates the expression of a battery of genes ass...
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