The structure and function of tenascins in the nervous system.

doi:10.1016/s0945-053x(00)00136-0

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Article

The structure and function of tenascins in the nervous system.

Matrix biology : journal of the International Society for Matrix Biology - 1 Feb 2001

Joester A, Faissner A

Abstract excerpt

The tenascins are a family of large extracellular matrix glycoproteins that comprise five known members. Three of these, tenascin-C (TN-C) tenascin-R (TN-R) and tenascin-Y (TN-Y) are expressed in specific patterns during nervous system development and are down-regulated after maturation. The expression of TN-C, the best studied member of the family, persists in restricted areas of the nervous system that exhibit...

Topics

Alternative Splicing
Animals
Genetic Variation
Humans
Nervous System Physiological Phenomena
Protein Isoforms
Receptors, Antigen
Structure-Activity Relationship
Tenascin

Source

Open in PubMed

Identifiers

PMID: 11246000
DOI: 10.1016/s0945-053x(00)00136-0

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